William Casey Blake (born on August 23, 1973 in Des Moines, Iowa) is an American professional baseball player. Currently, Blake is a third baseman and plays for the Cleveland Indians of Major League Baseball's American League Central Division.

Prior to joining the Indians in , Blake played with the Toronto Blue Jays, Minnesota Twins and Baltimore Orioles. He alternated between playing at third base and first base before becoming a full-time third baseman with the Indians. In , Blake moved to right field to accommodate the Indians' signing of third baseman Aaron Boone, but has since moved back to third.

Blake was drafted twice prior to signing with the Blue Jays: in , he was taken during the 11th round by the Philadelphia Phillies; in , he was taken by the New York Yankees during the 45th round.